Two Cases of Lichen Nitidus Treated with Diphenylcyclopropenone Immunotherapy.
- Author:
Seung Dong LEE
1
;
Mi Yeon KIM
;
Seung Cheol BAEK
;
Dong HOUH
;
Dae Gyoo BYUN
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. dahfh@hfh.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Lichen nitidus;
Diphenylcyclopropene
- MeSH:
Alopecia Areata;
Hypersensitivity, Delayed;
Immunity, Cellular;
Immunotherapy*;
Lichen Nitidus*;
Lichens*;
Skin Diseases;
Warts
- From:Korean Journal of Dermatology
2001;39(12):1432-1434
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lichen nitidus is a rare, usually asymptomatic chronic inflammatory dermatosis composed of numerous, tiny, discrete, flesh colored, shiny papules. Since the disease is asymptomatic and self-limiting, the specific treatment is not required in most cases. But when the lesion is generalized, symptomatic, persistent, interfering with outlook, the treatment is required. Diphenylcyclopropene (DPCP), a potent contact sensitizing agent has been used for refractory wart and alopecia areata based on its ability to induce delayed hypersensitivity reaction or nonspecific cell-mediated immunity. We report two cases of lichen nitidus improved after topical DPCP application.
