The correlation between coronary artery plaque & perivascular adipose tissue parameters and non-alcoholic fatty liver disease
10.3969/j.issn.1002-1671.2024.05.010
- VernacularTitle:冠状动脉斑块及血管周围脂肪组织参数与非酒精性脂肪肝的相关性研究
- Author:
Ying TIAN
1
;
Chao WANG
;
Zhou WANG
;
Yongfeng REN
;
Jian LI
Author Information
1. 亳州市人民医院超声科,安徽 亳州 236800
- Keywords:
non-alcoholic fatty liver disease;
plaque;
vulnera-ble plaque;
perivascular adipose tissue
- From:
Journal of Practical Radiology
2024;40(5):725-728,740
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between non-alcoholic fatty liver disease(NAFLD)and coronary artery plaque and perivascular adipose tissue(PVAT)parameters.Methods A total of 119 patients who underwent liver ultrasound and coronary computed tomography angiography(CCTA)examination were selected and divided into NAFLD group(50 cases)and non-NAFLD group(69 cases).The types of coronary artery plaque,plaque vulnerability,plaque involvement length,plaque load,vascular remode-ling,degree of vessel stenosis,and parameters of pericoronary fat[pericoronary fat attenuation index(pFAI),pericoronary fat total volume of voxels(pFV),perivascular water attenuation index(PVWI)]were evaluated.The data were analyzed statistically.Results The incidence of vulnerable plaque in NAFLD group was higher than that in non-NAFLD group,and the difference was statistically significant(P＜0.001).The incidence of positive vascular remodeling in NAFLD group was higher than that in non-NAFLD group,the incidence of no remodeling was the opposite,and the differences were statistically significant(P=0.001).The incidence of non-calcified plaque in NAFLD group was higher than that in non-NAFLD group,and the incidence of calcified plaque was the opposite(P=0.011).The incidence of severe stenosis in NAFLD group was higher than that in non-NAFLD group,and the incidence of moderate stenosis was the opposite,with statistical significance(P=0.004).The pFAI and plaque load in NAFLD group was higher than that in non-NAFLD group,and the pFV value was lower than that in non-NAFLD group,with statistical significance(P＜0.001,P=0.029,P=0.002).Conclusion The incidences of vulnerable plaque,positive remodeling,non-calcified plaque,vascular severe stenosis,and plaque load are significantly higher in NAFLD group than those in non-NAFLD group.In addition,pFAI increases and pFV decreases in NAFLD group.
