Case report of children with Addison′s disease complicated by torsades de pointes
10.3760/cma.j.cn101070-20240313-00149
- VernacularTitle:儿童阿狄森氏病合并尖端扭转型室性心动过速1例
- Author:
Juanli WANG
1
;
Jian LI
;
Hongyu XIAO
;
Huan LI
;
Xi LEI
;
Tao WANG
Author Information
1. 西安交通大学附属儿童医院心血管内科，西安 710003
- Keywords:
Addison′s disease;
Torsade de pointes;
Q-T interval prolongation
- From:
Chinese Journal of Applied Clinical Pediatrics
2024;39(10):783-785
- CountryChina
- Language:Chinese
-
Abstract:
This article retrospectively analyzes the clinical data of a patient with Addison′s disease complicated by torsades de pointes treated in Children′s Hospital Affiliated to Xi′an Jiaotong University in July 2021.The patient, female, aged 12 years, was hospitalized multiple times due to recurrent seizures, syncope, and coma, and had been successively diagnosed with fulminant myocarditis, supraventricular tachycardia, etc.She was later transferred to Children′s Hospital Affiliated to Xi′an Jiaotong University, where during hospitalization, electrocardiogram (ECG) monitoring revealed torsades de pointes associated with the attacks.The ECG between attacks showed a prolonged Q-T interval, with the longest Q-Tc of 564 ms.Echocardiography suggested a slight enlargement of the left ventricle and reduced left ventricular ejection fraction.After a comprehensive examination, she was diagnosed with Addison′s disease.Treatment with intravenous Hydrocortisone for 3 days, followed by oral Hydrocortisone tablets, was administered sequentially.After treatment, symptoms such as syncope did not recur, and the Q-T interval gradually returned to normal.After continued treatment for 1 year, echocardiography revealed no abnormality.This report aims to enhance pediatricians′ understanding and research on the relationship between pediatric endocrine diseases and arrhythmias.
