Research progress on the role of immune cells in IgA nephropathy
10.3760/cma.j.cn101070-20230818-00107
- VernacularTitle:免疫细胞在IgA肾病中的作用研究进展
- Author:
Weiran ZHOU
1
;
Xuemei LIU
;
Linlin DONG
;
Hongxia ZHANG
Author Information
1. 山东大学附属儿童医院（济南市儿童医院）肾脏风湿免疫科，济南 250022
- Keywords:
IgA nephropathy;
Macrophage;
Dendritic cell;
B cell;
T cell
- From:
Chinese Journal of Applied Clinical Pediatrics
2024;39(6):477-480
- CountryChina
- Language:Chinese
-
Abstract:
IgA nephropathy is a common primary glomerular disease.Its pathogenesis is currently unclear.As an autoimmune disease, immune response is a key link in the onset of IgA nephropathy.Multiple immune cells are involved in the occurrence and development of IgA nephropathy.The impacts of different cell subpopulations of innate and adaptive immunity can lead to sustained immune damage directly or indirectly.This article elaborates on the role of immune cells in IgA nephropathy from two aspects, namely innate immunity and adaptive immunity, aiming to provide references for further research on IgA nephropathy.
