Focus on invasive Group A Streptococcal diseases and their risk factors based on a typical case
10.3760/cma.j.cn101070-20240131-00064
- VernacularTitle:关注侵袭性A族链球菌疾病及其高危因素
- Author:
Mengyang GUO
1
;
Jun LIANG
;
Siyu CHEN
;
Xiaojia ZHANG
;
Wei GAO
;
Jinghui JIANG
;
Kaihu YAO
Author Information
1. 国家儿童医学中心，首都医科大学附属北京儿童医院，北京市儿科研究所感染与微生物研究室，国家呼吸系统疾病临床医学研究中心，儿科学国家重点学科，儿科重大疾病研究教育部重点实验室，北京 100045
- Keywords:
Child;
Risk factor;
Epidemiology;
Group A Streptococcus;
Invasive Group A Streptococcus disease
- From:
Chinese Journal of Applied Clinical Pediatrics
2024;39(6):426-432
- CountryChina
- Language:Chinese
-
Abstract:
Group A Streptococci(GAS)can cause multiple diseases such as pharyngotonsillitis, scarlet fever, streptococcal toxic shock syndrome(STSS), necrotizing fasciitis, and so on, making it extremely difficult to monitor all GAS infections.Developed countries such as the United States and the United Kingdom have classified invasive GAS diseases/infections(iGAS) or certain specific types, such as STSS, as notifiable diseases.China only includes scarlet fever caused by GAS infections in the legal infectious diseases.Although case reports or clinical studies of STSS and necrotizing fasciitis in China can be found, there is a lack of investigation and summary on iGAS, and there are few materials to introduce its definition and diagnostic criteria.Based on a recently diagnosed typical case, this paper intends to introduce the definition and diagnostic criteria of iGAS adopted in the United States, the United Kingdom and other developed countries, as well as the valuable early manifestations and risk factors, and the incidence of iGAS.Given the epidemiological changes in GAS infections in recent years, this paper also emphasizes the importance of paying attention to GAS infections, especially iGAS, aiming to arouse the attention of China′s clinical doctors and urge them to carry out research on this group of diseases.
