Systematic evaluation on influence of local pressing on LMWH subcutaneous injection
10.3760/cma.j.issn.1674-2907.2016.35.022
- VernacularTitle:局部按压对低分子肝素皮下注射相关影响的系统评价
- Author:
Yanlin HUANG
1
;
Li FU
;
Yuemei LI
;
Jiangqiong CHEN
;
Weiwei XU
Author Information
1. 300211 天津医科大学第二医院护理部
- Keywords:
Low-molecular-weight-heparin ( LMWH);
Subcutaneous injection;
Pressing duration;
Bruising;
Meta analysis
- From:
Chinese Journal of Modern Nursing
2016;22(35):5114-5118,5119
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate, after subcutaneous injection of low-molecular-weight-heparin( LMWH) , the effect of whether pressing or not on bruising. Methods All controlled clinical trails about pressing duration after subcutaneous injection of LMWH were collected by searching Cochrane Library (CENTRAL), PubMed, EMbase, CNKI, and Chinese Biomedical Literature Database (CBM). Two researchers, working independently, extracted strictly and assessed the data by the bias risk evaluation tool of the Cochrane collaboration network, with the data combined and analyzed by RevMan 5. 3 software. Results Nine clinical controlled trials that were all Chinese literatures were included, in which 2 814 injections were reported in total in the pressing group while 2 801 ones in non-pressing group. It was shown in Meta analysis that for severe subcutaneous bleeding, RR=0.7, 95% CI(0.49-0.99), (P<0.05); subgroup analysis revealed that evaluation criterion of the outcome indicators was the sources of heterogeneity among the included studies, and the results supported the positive effect of not pressing. Conclusions Pressing duration has an impact on bruising after subcutaneous LMWH injections. No pressing after injection does not increase the incidence rate of local moderate or severe subcutaneous bleeding.
