Nutritional status of 15 children with progeria
10.3760/cma.j.cn112140-20230928-00230
- VernacularTitle:早老症患儿15例营养状况分析
- Author:
Yafang DU
1
;
Qi LONG
;
Jingjing WANG
;
Ming MA
;
Jianhua MAO
Author Information
1. 浙江大学医学院附属儿童医院临床营养科 国家儿童健康与疾病临床医学研究中心，杭州 310052
- Keywords:
Nutritional status;
Progeria;
Body composition;
Dietary survey
- From:
Chinese Journal of Pediatrics
2024;62(2):170-174
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the nutritional status of progeria, and to provide reference for scientific nutritional management of progeria.Methods:This cross-sectional study included 15 children with progeria who were treated at Children′s Hospital, Zhejiang University School of Medicine, between April 2022 and May 2023. Data of medical history, physical examination, laboratory tests, dietary survey and body composition were collected and analyzed.Results:Among 15 patients there were 7 males and 8 females, aged 7.8 (2.3, 10.8) years. Twelve of the 15 patients exhibited signs of malnutrition. A 24-hour dietary survey was carried out in 14 of them. The daily energy intake of 11 cases was below recommended levels. Carbohydrate intake was insufficient in 10 cases, protein intake was insufficient in 7 cases, and fat intake was insufficient in 12 cases. Deficiencies in calcium, magnesium, iron and zinc were noted in 13, 13, 9 and 10 cases, respectively. Body composition was determined by dual-energy X-ray absorptiometry in 8 cases, and the bone mineral density was below average in 5 of them.Conclusions:Malnutrition, characterized by reduced energy intake, micronutrient deficiencies, and alteration in body composition, is prevalent in children with progeria. Regular routine nutritional assessment and proper interventions may benefit their long-term health status.
