Treatment,Prevention and Challenges of MRBp Infection in the Resurgence of Pertussis

VernacularTitle:百日咳重现下MRBp感染的治疗、防控及面临的挑战
Author: Da XUE ¹ ; Zengguo WANG ; Kaichong JIANG ; Shuyue TANG
Author Information

1. 陕西中医药大学,陕西咸阳 712046
Keywords: whooping cough; Bordetella pertussis; macrolide-resistant Bordetella pertussis; diagnosis and treatment; prevention and control
From: Journal of Modern Laboratory Medicine 2024;39(4):1-4,22
CountryChina
Language:Chinese
Abstract: Whooping cough,caused by Bordetella pertussis(Bp)infection,is an acute respiratory infectious disease in children transmitted through the air.Macrolide antibiotics have long been the first-line treatment for whooping cough.However,in recent years,macrolide-resistant Bordetella pertussis(MRBp)has been rarely reported outside China.The high prevalence of MRBp in China adds to the global challenge of whooping cough resurgence.The research firstly reports the emergence of clinical MRBp strains in China and has conducted extensive research in this field.This paper focuses on discussing the progress and challenges in the diagnosis,treatment and prevention of MRBp based on historical and recent studies.