Histomorphometry and stability analysis of early loaded implants with two different surface conditions in beagle dogs.
- Author:
Dong Seok KIM
1
;
Dae Gon KIM
;
Chan Jin PARK
;
Lee Ra CHO
Author Information
- Publication Type:Original Article
- Keywords: Oxidized implant; Histomorphometry; Early loading
- MeSH: Animals; Crowns; Dental Implants; Diet; Dogs; Mandible; Titanium
- From:The Journal of Advanced Prosthodontics 2009;1(1):10-18
- CountryRepublic of Korea
- Language:English
- Abstract: STATEMENT OF PROBLEM: Despite an improved bone reactions of Mg-incorporated implants in the animals, little yet has been carried out by the experimental investigations in functional loading conditions. PURPOSE: This study investigated the clinical and histologic parameters of osseointegrated Mg-incorporated implants in early loading conditions. MATERIAL AND METHODS: A total of 36 solid screw implants (diameter 3.75 mm, length 10 mm) were placed in the mandibles of 6 beagle dogs. Test groups included 18 Mg-incorporated implants. Turned titanium implants served as control. Gold crowns were inserted 4 weeks after implant placement and the dogs were immediately put on a food diet. Implants were observed for 10 weeks after loading. Radiographic assessments and stability tests were performed at the time of fixture installation, 2nd stage surgery, 4 weeks after loading, and 10 weeks after loading. Histological observations and morphometrical measurements were also performed. RESULTS: Of 36 implants, 33 displayed no discernible mobility, corresponding to successful clinical function. There was no statistically significant difference between test implants and controls in marginal bone levels (P = .46) and RFA values. The mean BIC% in the Mg-implants was 54.5 +/- 8.4%. The mean BIC% in the turned implant was 45.3 +/- 12.2%. These differences between the Mg-implant and control implant were statistically significant (P = .005). CONCLUSIONS: The anodized, Mg-incorporated implant demonstrated significantly more bone-to-implant contact (BIC) in early loading conditions. CLINICAL IMPLICATIONS: The results of this study in beagle dogs suggest the possibility of achieving predictable stability of early loaded free-standing dental implants with Mg-incorporated surface.