Colorectal Neoplasm in Asymptomatic Average-risk Koreans: The KASID Prospective Multicenter Colonoscopy Survey.
- Author:
Hye Won PARK
1
;
Jeong Sik BYEON
;
Suk Kyun YANG
;
Hyun Soo KIM
;
Won Ho KIM
;
Tae Il KIM
;
Dong Il PARK
;
Young Ho KIM
;
Hyo Jong KIM
;
Moon Sung LEE
;
Il Kwon CHUNG
;
Sung Ae JUNG
;
Yoon Tae JEEN
;
Jai Hyun CHOI
;
Hwang CHOI
;
Kyu Yong CHOI
;
Dong Soo HAN
;
Jae Suk SONG
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jsbyeon@amc.seoul.kr
- Publication Type:Multicenter Study ; Original Article
- Keywords:
Prevalence;
Colonoscopy;
Colorectal neoplasms;
Korea;
Mass screening
- MeSH:
Adult;
Aged;
Colonoscopy;
Colorectal Neoplasms;
Hospitals, University;
Humans;
Incidence;
Korea;
Male;
Mass Screening;
Nitriles;
Prevalence;
Prospective Studies;
Pyrethrins;
Risk Factors
- From:Gut and Liver
2009;3(1):35-40
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: The incidence of colorectal cancer is increasing in Korea, but the epidemiology of colorectal neoplasm is not clearly defined. We aimed to elucidate the prevalence of colorectal neoplasm in average-risk Koreans and explore the underlying risk factors. METHODS: A large-scale, multicenter, prospective study was conducted. Of the 19,460 subjects who underwent colonoscopy at 11 university hospitals, we analyzed 3,951 consecutive asymptomatic adults with no risk factors for colorectal cancer. RESULTS: The subjects were aged 52.1+/-11.6 years (mean+/-SD) and 60.1% of them were men. The prevalences of colorectal neoplasm and advanced neoplasm were 33.3% and 2.2%, respectively. The prevalence of a neoplasm increased with age (trend: p<0.001) and was higher in males (p<0.001). The prevalence of a proximal neoplasm was higher in subjects with a distal neoplasm than in those without a distal neoplasm (11.9% vs. 5.4%, p<0.001). However, 150 (52.1%) of the 288 subjects with a proximal neoplasm had no distal neoplasm. CONCLUSIONS: The overall prevalence of colorectal neoplasm in asymptomatic average-risk Koreans is comparable with that in Western countries. Being male and older are associated with a higher risk of colorectal neoplasm. Over half of proximal neoplasms are not associated with any distal sentinel lesions.
