Wet Synthesis and Characterization of Fluoride-substituted Hydroxyapatite
10.3321/j.issn:1001-5515.2001.02.002
- VernacularTitle:含氟羟基磷灰石的合成与性能研究
- Author:
Yumei ZHANG
1
;
Tao FU
;
Kewei XU
;
Hong AN
Author Information
1. Xi'an Jiaotong University
- From:
Journal of Biomedical Engineering
2001;18(2):173-176
- CountryChina
- Language:Chinese
-
Abstract:
Hydroxyapatite and fluoride-substituted hydroxyapatite powders are synthesized by wet method, compacted into pallets and subjected to heat treatment at 300, 600, 900℃ respectively. Analysis of the fluoride-substituted hydroxyapatites and HA by FTIR spectroscopy indicated that with the increasing of sintering temperatures, the phase-pure fluoride-substituted hydroxyapatite and stoichiometric hydroxyapatite could be got. According to the X-ray diffraction analysis, the fluoride-substituted hydroxyapatite is less stable for decomposing into β-Ca3(PO4)2 at the temperature of 900℃. The in vitro bioactivity of the fluoride-substituted hydroxyapatites and hydroxyapatite heat treated at 900℃ was assessed by immersion testing in simulated body fluid (SBF). Both scanning electron microscopy (SEM) analysis and ionic solution changes (Ca2+) demonstrated that the low fluoride content apatite could induce a surface bonelike apatite layer formation.
