The Research of Receptor-mediated Drug Carrier
10.3321/j.issn:1001-5515.2001.01.034
- VernacularTitle:受体介导的蛋白多肽靶向药物载体的应用研究
- Author:
Hao DING
1
;
Anren KUANG
Author Information
1. The First University Hospital West China University of Medical Science
- From:
Journal of Biomedical Engineering
2001;18(1):129-132
- CountryChina
- Language:Chinese
-
Abstract:
One way to increase the concentration of drug in diseased tissue is to attach drug to a suitable carrier such as proteinor peptides,which can improve the pharmacokinetic properties of drug and decrease it's side-effect on normal tissue. The developments of receptor-mediated transporting of drug assotiated with proteinor peptides are reviewed in this paper. The most frequently used receptors and drug carriers and the bonds between the drug and the carrier are introduced. The machanism of transporting and the factors that affect the efficiency of the drug carrier are discussed as well.
