A Computer Image Processing System to Analyze Endothelial Cell-Platelet Thrombus Quantitatively
10.3321/j.issn:1001-5515.2001.01.011
- VernacularTitle:内皮细胞-血小板血栓定量分析系统
- Author:
Hengyi ZHANG
1
;
Xiaoxiang ZHENG
Author Information
1. 浙江大学
- From:
Journal of Biomedical Engineering
2001;18(1):38-41
- CountryChina
- Language:Chinese
-
Abstract:
A Computer Image Processing System for cone-pl ate rolling model which forms endothelial cell-platelet thrombus in vitro is p resented in this paper. Some parameters such as endothelial cell shape parameter s(area, perimeter, long axial length, short axial length, angle of orientation, and shape index), platelet adhesion coverage, platelet adhesion density, diffusi vity and surface reactivity constant are measured during the reaction of endothe lial cells and platelet under the fluid shear stress condition. The invitro th rombus model and the corresponding quantitative analysis system is useful in the studies on endothelial cells-platelets interaction and mechanism of thrombosis and atherosclerosis.