The Sieving Performance of a New Polyethersulfone Hollow Fiber Plasma Fractionation Membrane
10.3321/j.issn:1001-5515.2001.01.002
- VernacularTitle:一种新聚醚砜中空纤维血浆成分分离膜的
- Author:
Changsheng ZHAO
1
;
Ting LIU
;
Zhongping LU
;
Liping CHENG
;
Xixun YU
;
Yilun YUE
Author Information
1. Sichuan University
- From:
Journal of Biomedical Engineering
2001;18(1):5-8
- CountryChina
- Language:Chinese
-
Abstract:
Plasma fractionation membrane is very important in double filtration plasmapheresis. We studied a new polyethersulfone hollow f iber membrane plasma fractionator and evaluated the effect of time, transmembran e pressure (TMP) and mean shear rate on the sieving coefficient (SC) during memb rane plasma fractionation. The sieving coefficients of various proteins reached their maximum values at 40 min at the plasma flow rate QI=30ml/min and plasma filtrated flow rate QF=20ml/min. The QF increased with the increase of TMP, and the point of the intersection of the curve of the QF vs. TMP and the SC vs . TMP was regarded as the ideal condition for plasma fractionation. The plasma filtrated rate PFR=QF/QI=0.6～0.7. The TMP changed with the change of the mea n shear rate, and the mean shear rate had little effect on the SC. The data is o f significance to the application of plasma fractionation membrane.
