Blinding Designs and Critical Issues in Acupuncture Clinical Trials
- VernacularTitle:针刺临床研究中的盲法及其关键问题
- Author:
Tinglan LIU
1
;
Haoran ZHANG
;
Xiaoyu LIU
;
Zhiyi XIONG
;
Chengyi SUN
;
Shiyan YAN
Author Information
- Keywords: Blinding; Blinding assessment; Sham acupuncture; Clinical trials; Acupuncture
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(7):1765-1770
- CountryChina
- Language:Chinese
- Abstract: Blinding is an important method to control the measure bias in clinical trials.As a complex and invasive intervention,acupuncture has more difficulty in blinding implementation compared to drugs and has a higher risk of unblinding breakage.This article provides an overview of the blinding in acupuncture clinical study and summarized the key aspects,including:there is no standard for the application and reporting of sham acupuncture design and blinding measures,appropriate sham acupuncture devices still need to be developed,currently there are no effective methods of operator blinding,blinding assessment has not been given due attention,sham acupuncture design should be standardized and reported.Researchers should conduct further studies to address critical questions and challenges to provide methodological support to improve and promote the quality of acupuncture clinical research.
