Chinese and Western Medicine Control Strategies for Anthracycline Cardiotoxicity
10.11842/wst.20230607004
- VernacularTitle:蒽环类药物心脏毒性的中西药防治策略
- Author:
Jun QIAN
1
;
Shumin ZHANG
;
Huixin QIU
;
Sitong LIU
;
Yanru DENG
;
Lexin SHU
Author Information
1. 天津中医药大学中药学院 天津 301617
- Keywords:
Anthracyclines;
Cardiotoxicity;
Prevention and control strategy;
Western medicine;
Traditional Chinese medicine;
Drug combination
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2024;26(7):1706-1714
- CountryChina
- Language:Chinese
-
Abstract:
Cardiac toxicity of anthracycline greatly limit its clinical use,to explore the rule of anthracycline cardiotoxicity and prevention and control strategies of Chinese and western medicine,this paper through the literature search mechanism and drugs is summarized,the mechanism can be divided into oxidative stress,inflammatory reaction,myocardial cell autophagy and DNA damage four categories,the prevention and treatment of western medicine to dc prosamine,ACEI,ARB is given priority to,Chinese medicine can be divided into single medicine,by prescription and proprietary Chinese medicine.On this basis,the combination drug is discussed to prevent cardiotoxicity,and the theoretical basis and research status of the combined application of western medicine,traditional Chinese medicine and Chinese and western medicine are introduced.The results show that it has good feasibility and safety,and can provide reference for the clinical treatment strategy of anthracycline chemotherapy drugs.