Research Progress on Animal Models of Attention Deficit Hyperactivity Disorder
- VernacularTitle:注意缺陷多动障碍动物模型研究进展
- Author:
Yongting ZHANG
1
;
Rongyi ZHOU
;
Bingxiang MA
;
Xinyue XIE
;
Xueying DING
;
Qing HE
;
Yuyan ZHANG
Author Information
- Keywords: Attention deficit hyperactivity disorder; Animal model; Genes; Environmental factors; Neurodevelopmental disorder
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(6):1563-1573
- CountryChina
- Language:Chinese
- Abstract: Attention deficit disorder(ADHD)is a common neurodevelopmental disorder in childhood,which seriously affects the physical and mental health of children.Up to now,the etiology and pathogenesis of ADHD are not clear,which is also the focus of global research.Animal model is an important carrier for basic research of ADHD,but the use of ADHD animal model is still controversial.This paper introduces the main emerging ADHD animal models in the world in recent years and analyzes their advantages and disadvantages.The genetic model,environmental induction model and neurodevelopmental disorder model are introduced and summarized from three aspects:surface validity,construct validity and predictive validity.The purpose of this study is to find a suitable animal model for the basic research of ADHD and to provide reference for the basic research of ADHD in China.
