Evaluation of Atractylodis macrocephalae Rhizoma Decoction Pieces Quality Grade Based on Appearance Characteristics and Atractylodes Lactone and Total Polysaccharide
10.11842/wst.20230413005
- VernacularTitle:基于白术内酯及总多糖结合外观性状评价白术饮片等级质量
- Author:
Hongzhi DU
1
;
Ying ZHENG
;
Zhilin CHEN
;
Minjie ZHANG
;
Wei LI
Author Information
1. 贵州中医药大学药学院 贵阳 550025
- Keywords:
Atractylodis macrocephalae Rhizoma decoction pieces;
Atractylodes lactone;
Total polysaccharide;
Appearance characteristics;
Grade study
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2024;26(6):1537-1545
- CountryChina
- Language:Chinese
-
Abstract:
Objective Through the study of different grades for Atractylodis macrocephalae Rhizoma decoction pieces,improve the quality evaluation method,and provide theoretical basis for the classification of Atractylodis macrocephalae Rhizoma.Methods According to the traditional classification,the Atractylodis macrocephalae Rhizoma decoction pieces was divided into three grades.By HPLC and UV method,the determination of atractylodes lactone Ⅰ,Ⅱ,Ⅲ and the content of total polysaccharide for 36 batches of different grades of Atractylodis macrocephalae Rhizoma decoction pieces.According to the 2020 edition of Chinese pharmacopoeia,the correlation between the appearance traits of different grades of Atractylodis macrocephalae Rhizoma decoction pieces and the internal quality control indexes was analyzed.Results According to the appearance characters,multiple quality control index of content determination,through the principal component analysis,cluster analysis and so forth.The quality of first-grade decoction pieces of Atractylodis macrocephalae Rhizoma is significantly better than the second-grade and third-grade decoction pieces(P<0.05),and there is no significant difference between second-grade and third-grade decoction pieces(P>0.05).As a result,the Atractylodis macrocephalae Rhizoma decoction pieces can be divided into two grades,different grades with the content of atractylodes lactone and total polysaccharide were positively correlated.Conclusion The classification of Atractylodis macrocephalae Rhizoma decoction pieces based on multiple quality control indexes combined with appearance characters can provide a scientific basis for the quality control and grade study of this decoction piece.
