Discussion on the Pathogenesis and Microcosmic Syndrome Differentiation of Spasmolytic Polypeptide Expressing Metaplasia Based on the Theory of"Spleen Deficiency and Evil Stagnation"
- VernacularTitle:基于"脾虚邪滞"理论探讨胃解痉多肽表达化生中医病机与微观辨证
- Author:
Xinlong LI
1
,
2
;
Siyi LI
;
Penhui YANG
;
Quiyue LI
;
Huafeng PAN
Author Information
- Keywords: Spasmolytic Polypeptide Expressing Metaplasia; Microcosmic syndrome differentiation; Gastric precancerous lesions; Jianpi huayu jiedu therapy
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(5):1104-1110
- CountryChina
- Language:Chinese
- Abstract: Gastric Precancerous Lesions(GPL)have the risk of developing gastric cancer,and Spasmolytic Polypeptide Expressing Metaplasia(SPEM)is the initial step of GPL,which has the risk of malignant progression to gastric precancerous lesions.Currently,the exploration of the pathogenesis during this metaplasia stage remains incomplete.Traditional Chinese Medicine(TCM),relying on its solid theoretical foundation and abundant resources of Chinese medicinal materials,possesses unique advantages in the prevention and treatment of GPL.Based on the theory of"spleen deficiency and evil stagnation",we conducts microcosmic syndrome differentiation analysis from the pathophysiological state,markers,and signal pathways of the disease,and proposes to invigorate the spleen and remove blood stasis.The detoxification method is used for treatment,and its feasibility is analyzed in combination with the literature,in order to provide new ideas and strategies for the TCM treatment of SPEM.
