Relationship Between Neuroinflammation and Alzheimer's Disease and the Regulatory Mechanism of Acupuncture and Moxibustion
- VernacularTitle:神经炎症与阿尔茨海默病的关系及针灸调控机制研究进展
- Author:
Lu LEI
1
;
Peiran LYU
;
Yao ZHAO
;
Yue LIANG
;
Haifa QIAO
;
Qi LIU
;
Ning ZHANG
Author Information
- Keywords: Acupuncture; Alzheimer's disease(AD); Neuroinflammation; Research progress
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(4):1028-1035
- CountryChina
- Language:Chinese
- Abstract: Alzheimer's disease(AD)is a common neurodegenerative disease.Neuroinflammation is one of the important pathological mechanisms of AD.The generation of AD neuroinflammation is closely associated with Aβ deposition,Tau phosphorylation,glial polarization and activation of inflammasome.Acupuncture and moxibustion have such effect on the improvement of AD neuroinflammation,which can relieve neuroinflammation by regulating the polarization of microglia and astrocytes,reducing the release of inflammatory mediators,so as to delay the pathological process of AD.This article reviews the neuroinflammatory mechanism of AD and the research progress of acupuncture and moxibustion regulating AD neuroinflammation,in order to provide a theoretical basis and idea reference for the clinical and basic research of acupuncture and moxibustion in the prevention and treatment of AD.
