Prevalence characteristics of influenza viruses in children in Beijing during 2014-2015 and 2015-2016 influenza seasons
10.3760/cma.j.issn.0578-1310.2016.08.005
- VernacularTitle:北京地区2014-2015年和2015年-2016年流感流行季儿童流感流行特征分析
- Author:
Yu SUN
1
;
Runan ZHU
;
Fang WANG
;
Jie DENG
;
Linqing ZHAO
;
Run TIAN
;
Yuan QIAN
Author Information
1. 100020,首都儿科研究所病毒研究室儿童病毒病病原学北京市重点实验室
- Keywords:
Influenza,human;
Epidemiology;
Child
- From:
Chinese Journal of Pediatrics
2016;54(8):582-586
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the prevalence characteristics of influenza viruses in children in Beijing during 2014-2015 and 2015-2016 influenza seasons.Method Throat swabs were collected weekly from children with influenza-like illnesses who visited in Children's Hospital affiliated to Capital Institute of Pediatrics during the period from September 2014 to May 2016.Influenza viruses A and B viruses were detected by real-time RT-PCR,followed by identification of H3 N2,H 1N 1 pdm,B/Victoria-like and B/ Yamagata-like.The prevalence characteristics of influenza viruses was estimated by means of descriptive statistics.The t test and chi-square test were used to compare median age and gender ratio of infected children among different types of influenza viruses.Result Out of 1 821 throat swabs collected,139 (7.6％) were positive for H3N2 and 43 (2.4％) for H1N1pdm and 204 (11.2％) for influenza B virus,including 108 for B/Victoria-like and 96 for B/Yamagata-like.The median age of H1N1pdm infected children ((3.3 ± 2.2) years) was significantly younger than that of H3N2 ((4.7 ± 3.2) years) and influenza B virus ((4.9 ± 2.8) years) (H1 N1 pdm vs.H3N2:t =2.848,P =0.002;H1N1 pdm vs.influenza B,t =3.682,P =0.000).Two epidemic peaks were presented in 2014-2015 influenza season,dominated definitely by H3N2 and B/Yamagata-like,respectively,while one delayed peak started at the 51st week,2015,co-circulated with H3N2,Hl Nlpdm and influenza B viruses,among which B/Victoria-like virus was predominant during the 2015-2016 season.Conclusion Prevalence characteristics of influenza viruses are different between 2014-2015 and 2015-2016 influenza seasonal epidemics in children in Beijing.It is important to monitor the genetic variations of influenza viruses and to keep close attention to influenza B virus as well as influenza A virus.
