Clinical features and therapy of persistent bacterial bronchitis in 31 children
10.3760/cma.j.issn.0578-1310.2016.07.011
- VernacularTitle:持续性细菌性支气管炎31例诊治分析
- Author:
Junran SHI
1
;
Jinrong LIU
;
Huimin LI
;
Wei WANG
;
Shunying ZHAO
Author Information
1. 石家庄市妇幼保健院儿内科
- Keywords:
Bronchitis;
Chronic cough;
Child
- From:
Chinese Journal of Pediatrics
2016;54(7):527-530
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features and therapy of persistent bacterial bronchitis (PBB).Method A retrospective review of 31 patients with PBB from Octorber 2010 to May 2014 in Department 2 of Respiratory Diseases in Beijing Children's Hospital was undertaken.Result (1) The patients (17 boys and 14 girls) were 6 months to 3 years old.The main complaint was chronic wet cough (＞4 weeks);13 cases had fever and 25 cases had wheezing.Rattle was heard on auscultation in all patients.(2) Chest X ray showed an increase in bronchovascular markings in all cases,accompanied by patchy infiltration in 6 cases.The high resolution computed tomography (HRCT) demonstrated bronchial wall thickening in 25 cases,associated with peri-bronchial patchy infiltration in 18 cases,with organized pneumonia in 7 cases (atelectasis in 5 cases).Centrilobular nodules and ground-glass opacity were observed in the remaining 6 patients.(3) Purulent secretion was seen in endobronchial cavity by bronchoscopy.Streptococcus pneumoniae was isolated from sputum culture or bronchoalveolar lavage fluid culture in 16 patients.(4) Patients recovered completely after over 2 weeks' treatment with amoxicillinclavulanate or the second and third generation cephalosporin (including enzyme inhibitors) in 28 cases,carbapenems,teicoplanin,linezolid in 1 case respectively.Conclusion PBB often occurred in 3 years old or younger patients and had chronic wet cough for more than 4 weeks,fever and wheezing.HRCT may reveal bronchial wall thickening,respiratory secretions culture may reveal Streptococcus pneumoniae.Most of patients recovered completely after over 2 weeks'treatment with amoxicillin-clavulanate or the second or third generation cephalosporins (including enzyme inhibitors).
