To Explore the Mechanism of Intestinal Mucosal Immunity and Ulcerative Colitis in Chinese Medicine from Perspective of"Spleen as the Defense"
- VernacularTitle:从"脾为之卫"理论探讨肠道黏膜免疫与溃疡性结肠炎的中医机制
- Author:
Xiangxue MA
1
;
Yongtian WEN
;
Xiaolan YIN
;
Beihua ZHANG
;
Xudong TANG
Author Information
- Keywords: "Spleen as the defense"; Spleen deficiency; Intestinal mucosal immunity; Ulcerative colitis
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(3):640-645
- CountryChina
- Language:Chinese
- Abstract: The pathogenesis of ulcerative colitis(UC)is still unclear,and the pathogenesis based on intestinal mucosal immune imbalance is now widely recognized."Spleen as the defense"refers to the function of the spleen to protect the body and defend against pathogenic factors,which is highly consistent with modern mucosal immunology theory.The abnormal function of"Spleen as the defense"is the key reason for the immune imbalance of UC intestinal mucosa.In this paper,"spleen as the defense"as the starting point,to explore the mechanism of UC intestinal mucosal immune dysfunction,to consolidate the theoretical basis for the treatment of UC based on spleen,and to provide a theoretical basis for the treatment of UC from the perspective of restoring intestinal mucosal immune homeostasis.
