The Ideas and Methods of Treatment Related to the Spleen Theory on Precancerous Lesions of Gastric Carcinoma
10.11842/wst.20230129001
- VernacularTitle:从脾论治胃癌前病变的思路与方法
- Author:
Han WANG
1
;
Ping WANG
;
Yichen WANG
;
Xudong TANG
Author Information
1. 北京中医药大学研究生院 北京 100029
- Keywords:
Precancerous lesion of gastric cancer;
Inflammation-cancer transformation;
Traditional Chinese medicine;
Spleen deficiency
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2024;26(3):634-639
- CountryChina
- Language:Chinese
-
Abstract:
Precancerous lesion of gastric carcinoma(PLGC)is a critical component of the occurrence,development,and metastasis of the"inflammation-cancer transformation".Traditional Chinese medicine(TCM)is characterized by a unique mode of diagnosis and treatment which adopts a holistic concept to differentiate and treat syndromes.With this mode,it can improve symptoms in patients,enhance the quality of their lives and elevate the histopathological performance.The pathogenic factors of PLGC are mostly related to spleen,among which the weakness of spleen and stomach is the pathogenetic basis of it.Over time,dampness,phlegm and blood stasis will accumulate in the body,causing local lesions.Spleen deficiency is associated with various development mechanisms of PLGC,including the gastric mucosal inflammation,intragastric flora,gastric mucosal barrier,immune function,energy metabolism,and gastric mucosal secretion.To treat PLGC from the perspective of the spleen theory,physicians should take steps to reinforce healthy Qi to eliminate pathogenic factors,give equal consideration to deficiency and excess,and harmonize the center to restore the balance in the viscera,which will invigorate the spleen and stomach,resolve dampness,clear heat and regulate qi and blood at the same time.The differentiation of the holistic and local syndromes should be combined and the treatment with drugs should take both diseases and syndromes into consideration.
