Mechanism of the Tongfu Therapy for the Treatment of Ischemic Stroke Based on"Brain-gut Interaction"
- VernacularTitle:基于"脑肠互动"探讨通腑法治疗缺血性中风的机制
- Author:
Chenfei HE
1
,
2
;
Chiyuan MA
;
Xiangzhe LIU
Author Information
- Keywords: Ischemic stroke; Tongfu therapy; Brain-gut interaction; Gut microbiota; Brain-gut peptide
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(3):617-621
- CountryChina
- Language:Chinese
- Abstract: Ischemic stroke is the leading cause of disability in China,and treatment options are still very limited.The method of dredging Fu-organs has been proved to have a significant effect in the treatment of ischemic stroke,but its mechanism is not clear.With the progress of brain-gut communication research,more and more evidence shows that brain-gut communication plays an important role during ischemic stroke.Based on the theory of"brain-gut interaction",this paper discusses the mechanism of Tongfu method in the treatment of ischemic stroke,and discusses the intestinal flora,brain-gut peptide,intestinal metabolites,intestinal mucosal barrier and other aspects.It is concluded that Tongfu method can treat ischemic stroke by regulating intestinal flora,brain-gut peptide content,intestinal metabolite content and repairing intestinal mucosal barrier.In order to provide more ideas for elucidating the mechanism of Tongfu method in the treatment of ischemic stroke,it has very important theoretical and clinical value.
