The Development of Kolomark(TM), A Korean Radio-opaque Marker for Measuring Colon Transit Time.
- Author:
Jee Eun KIM
1
;
Poong Lyul RHEE
;
Young Ho KIM
;
In Kyung SUNG
;
Sang Goon SHIM
;
Hee Jung SON
;
Jae Jun KIM
;
Kwang Cheol KOH
;
Seung Woon PAIK
;
Jong Chul RHEE
;
Kyoo Wan CHOI
;
Hyo Keun LIM
;
Soo Won SUH
Author Information
1. Division of Gastroenterology, Samsung Medical Center Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Colon transit time;
Radio-opaque marker;
Sitzmarks;
Kolomark(TM)
- MeSH:
Colon*;
Constipation;
X-Ray Film
- From:Korean Journal of Gastrointestinal Motility
1999;5(2):136-139
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Colon transit time is a useful method for assessing colonic motor function and classifying the type of idiopathic chronic constipation. Among various methods, a radio-opaque marker study is a simple, reproducible and economical method. The commonly used marker, Sitzmarks(R)(Konsyl Pharmaceuticals Inc. Texas) had limitations in its use due to expensiveness and difficulty in importation. We thought that a new domestic marker comparable to Sitzmarks(R) was necessary and we developed Kolomark (Korean colon marker)(TM). The radio-opaqueness of Kolomark(TM) was compared to that of Sitzmarks(R). METHODS: In two 1000ml of beakers, 350ml of rice-gruel, several chicken-bones and ten rings of Sitzmarks(R) and Kolomark(TM) were mixed separately. Then, X-ray films of the two beakers were taken. The digital image file was analyzed by image(R), a medical image processing program, and the value of pixels were obtained. These were repeated five times. RESULTS: The mean value of pixel of Kolomark(TM) was much lower than that of Sitzmarks(R). The difference between background or beaker and Kolomark(TM) was much greater than that of Sitzmarks. CONCLUSION: Kolomark(TM), a Korean colon marker which is more radio-opaque and cheaper than Sitzmarks(R) is developed and further study is needed to prove its clinical usefulness.
