Associations between the diet-related inflammation indices and digestive system cancer:a narrative review of epidemiological studies
10.3969/j.issn.1672-8467.2024.03.016
- VernacularTitle:饮食相关炎症指数与消化系统恶性肿瘤发病关系的流行病学研究进展
- Author:
Jing-Yu TAN
1
,
2
;
Yan ZHANG
;
Jun CHEN
;
Dan-Ni YANG
;
Yi-Xin ZOU
;
Wan-Shui YANG
;
Yong-Bing XIANG
Author Information
1. 上海交通大学医学院公共卫生学院 上海 200025
2. 上海市肿瘤研究所流行病学研究室 上海 200032
- Keywords:
diet-related inflammatory indices;
digestive system cancer;
inflammation;
prospective cohort study;
epidemiology
- From:
Fudan University Journal of Medical Sciences
2024;51(3):404-414
- CountryChina
- Language:Chinese
-
Abstract:
The inflammatory effect of dietary is strongly related to the development of cancer,therefore,the diet-related inflammatory index was developed as a methodological tool to investigate the relationship between dietary,inflammation and tumors.In this paper,we summarized the results on diet-related inflammatory indices and common cancers of the digestive system based on relevant cancer epidemiological studies.The available epidemiological evidence suggests that pro-inflammatory diet is associated with an increased risk of gastrointestinal malignancies,with the strongest association with colorectal cancer,followed by esophageal and gastric cancers,and then pancreatic cancer,and the least evidence of studies with liver cancer.Among these studies,the level of evidence for esophageal cancer is lower than colorectal cancer,the study of gastric cancer has gender differences and problems in adjusting for confounders,and the study of pancreatic cancer has heterogeneous results.In view of the current research progress and deficiencies,prospective studies or population-based cohort studies,as well as strengthening nutritional epidemiological studies related to common tumors such as liver cancer could be considered in the future.This review is expecting to provide basic information and scientific basis for strengthening the related healthy eating behavior promotion in the prevention and control of digestive system tumors.
