Pattern adaptation of relay cells in the lateral geniculate nucleus of binocular and monocular vision-deprived cats
10.3321/j.issn:0371-0874.2000.03.012
- VernacularTitle:双眼和单眼视觉剥夺猫外膝体细胞的图形适应
- Author:
Wei WANG
1
;
Tian-De SHOU
Author Information
1. 中国科学技术大学
- Keywords:
pattern adaptation;
visual deprivation;
lateral geniculate nucleus;
grating;
cat
- From:
Acta Physiologica Sinica
2000;52(3):230-234
- CountryChina
- Language:Chinese
-
Abstract:
To test whether the pattern adaptation in thalamus is dependent upon postnatal visual experience during early life, the responses of relay cells to prolonged drifting grating stimulation were recorded extracellularly from the dorsal lateral geniculate nucleus (dLGN) of cats reared with binocular and monocular lid suture. In binocular vision-deprived cats, 68% of cells recorded showed significant adaptation to prolonged grating stimuli within 30 s, with a mean response decrease of 33%, and then stabilized gradually. This adaptation was stronger than that of relay cells in normal cats. In monocular vision-deprived cats, 53% of the cells driven by the deprived eye showed similar adaptation as did 44% of the cells driven by the non-deprived eye. These results indicate that pattern adaptation could be maintained or even enhanced after visual deprivation in early life. It is suggested that pattern adaptation is a general and intrinsic property of the dLGN cells, which may be mainly determined by genetic factors.
