Research progress of tumor infiltrating lymphocytes in the tumor microenvironment of hepatocellular carcinoma
10.13431/j.cnki.immunol.j.20240041
- VernacularTitle:肝细胞癌肿瘤微环境中肿瘤浸润淋巴细胞的研究进展
- Author:
Lishan PENG
1
;
Linting NING
;
Xian LIU
Author Information
1. 530200 南宁,广西中医药大学广西高发传染病中西医结合转化医学重点实验室
- Keywords:
Hepatocellular carcinoma;
Tumor microenvironment;
Tumor infiltrating lymphocytes
- From:
Immunological Journal
2024;40(3):315-320
- CountryChina
- Language:Chinese
-
Abstract:
Liver cancer is a malignant tumor with a high mortality rate.With the continuous development of targeted drugs,immunotherapy and other technological means,translational therapy has become a consensus in the treatment of advanced liver cancer.The liver's inherent immune tolerance,tumor tissue,and various immune components constitute a dynamically changing liver cancer microenvironment.The immune escape in the microenvironment of liver cancer is the main obstacle to current immunotherapy.Cellular immunity is an important component of anti-tumor immunity,and the status and function of immune cells are closely related to cancer prognosis.This article reviews the progress of tumor infiltrating lymphocytes in the tumor microenvironment of hepatocellular carcinoma,in order to benefit the exploring of targeted antitumor therapy.
