Absence of arterial duct in fetus: an autopsy analysis
10.3760/cma.j.cn112151-20201130-00876
- VernacularTitle:胎儿动脉导管缺如的尸体解剖分析
- Author:
Jianfeng SHANG
1
;
Dong CHEN
;
Wei FANG
;
Fei TENG
;
Yayan CUI
;
Wen FU
;
Wei YU
;
Fang DONG
;
Qian LI
Author Information
1. 首都医科大学附属北京安贞医院 北京市心肺血管疾病研究所病理科100029
- Keywords:
Congenital heart disease;
Absence of arterial duct;
Fetus
- From:
Chinese Journal of Pathology
2021;50(3):213-216
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the absence of congenital arterial duct in fetus and to improve the diagnostic accuracy.Methods:Four hundred cases of congenital heart disease diagnosed by echocardiography during pregnancy were examined the fetal cardiovascular malformation and visceral malformation, and the absence of arterial duct was analyzed.Results:There were 24(6%)cases of absence of arterial duct, including 19 cases of left aortic arch and five cases of right aortic arch. There were 21 cases with main pulmonary arteries and 3 cases without main pulmonary arteries and branches. There were 15 cases of pulmonary artery stenosis with absence of arterial duct and the major cardiovascular malformations included six cases of single ventricle, six cases of atrial septal defect, four cases of single atrium, four cases of right atrium isomerism, four cases of double outlet right ventricle, four cases of anomalous pulmonary venous drainage, three cases of tetralogy of Fallot, and three cases of persistent left superior vena cava. There were seven cases of pulmonary atresia with absence of arterial duct and with systemic-pulmonary collateral circulation. There was one case of tetralogy of Fallot with absent pulmonary valve and absent arterial duct and the pulmonary artery was dilated. There was one case of aortopulmonary septal defect with absent arterial duct, with normal pulmonary artery. There were also seven cases of asplenia, seven cases of pulmonary abnormality and seven cases of visceral inversion.Conclusions:The absence of arterial duct is often associated with congenital heart disease. Pulmonary atresia is often associated with systemic-pulmonary collateral circulation. The visceral malformations are related to the accompanying congenital cardiovascular malformations.
