Clinical and pathological observation of 4 cases of odontogenic primordial tumors
10.13315/j.cnki.cjcep.2024.07.008
- VernacularTitle:牙源性始基瘤4例临床病理学观察
- Author:
Lei ZHANG
1
;
Huiling LI
;
Shu XIA
;
PAKEZHATI·Seyiti
;
Sheng CHEN
;
Yan YANG
;
Chuanjin YE
;
Yanhong NI
;
Xiaofeng HUANG
Author Information
1. 南京大学医学院附属口腔医院/南京市口腔医院/南京大学口腔医学研究所口腔病理科,南京 210008
- Keywords:
odontogenic neoplasm;
primordial odontogenic tumour;
clinicopathological features;
immunohistochemistry;
prognosis
- From:
Chinese Journal of Clinical and Experimental Pathology
2024;40(7):705-709
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the clinicopathological features,diagnosis and differential diagnosis of the primordial odontogenic tumour(POT).Methods Clinical data of 4 cases of jawbone POT were collected.Imaging examination,HE,and immunohistochemical EnVision two-step staining was used to an-alyze their clinical and pathological characteristics,and relevant literatures were reviewed.Results The age arranged from 5 years to 21 years.2 cases were male and 2 case were female.There were 2 cases in maxilla and 2 cases in mandible.The clinical presentation was a slow growing painless mass.Cut sur-face of the tumor was appeared grayish yellow and grayish white,the tumor involved the crown of an unerupted tooth.The tumour consisted of a proliferation of spindled and stellate cells in myx-oid stroma.Surfaced by cuboidal to columnar epithelium forming papillary structures and invaginations.Calcification was observed in 2 cases.Conclusion POT is a rare benign mixed odontogen-ic tumor that is more common in children and adolescents.Mas-tering its characteristic histological morphology can make a cor-rect diagnosis.Local complete resection of the tumor has a good prognosis.
