Research Progress on Predictive Factors and Related Predictive Models for Anastomotic Leakage After Esophageal Cancer Surgery
10.3969/j.issn.1005-6483.2024.08.029
- VernacularTitle:食管癌术后吻合口瘘预测因子及相关预测模型的研究进展
- Author:
Hainan CHEN
1
;
Xuefeng LENG
Author Information
1. 610041 成都,四川省肿瘤临床医学研究中心 四川省肿瘤医院·研究所 四川省癌症防治中心 电子科技大学附属肿瘤医院胸外科
- Keywords:
after surgery for esophageal cancer;
anastomotic leakage;
predictive model
- From:
Journal of Clinical Surgery
2024;32(8):892-895
- CountryChina
- Language:Chinese
-
Abstract:
Anastomotic leakage is one of the most severe complications following esophagectomy.Research on predictive factors is crucial for its prevention.Blood markers such as C-reactive protein,white blood cell count,procalcitonin,and albumin levels are widely used due to their accessibility,but they have limitations in distinguishing anastomotic leakage from other postoperative infections.The assessment of blood supply to the anastomotic site,including factors like vessel length and diameter,is also readily obtainable and valuable in predictive models,though there is limited research in this area.The use of indocyanine green offers a more direct evaluation of blood supply,but its application is not widespread,and data acquisition is challenging.Preoperative comorbidities such as diabetes have been shown to delay wound healing and increase the risk of leakage;thus,it is recommended to include these factors in comprehensive studies.Although surgical techniques and the location of the anastomosis have been extensively studied,further exploration of these details is necessary.Researchers should integrate these factors to develop multifactorial predictive models,enabling the identification of high-risk patients preoperatively and the implementation of effective preventive measures to reduce the incidence of anastomotic leakage.
