XYY syndrome: a 13-year-old boy with tall stature.
10.6065/apem.2015.20.3.170
- Author:
Won Ha JO
1
;
Mo Kyung JUNG
;
Ki Eun KIM
;
Hyun Wook CHAE
;
Duk Hee KIM
;
Ah Reum KWON
;
Ho Seong KIM
Author Information
1. Department of Pediatrics, Severance Children's Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul, Korea. kimho@yuhs.ac
- Publication Type:Case Report
- Keywords:
Growth disorders;
Sex chromosome disorders;
47, XYY syndrome
- MeSH:
Adolescent*;
Adult;
Androgen-Insensitivity Syndrome;
Estrogens;
Growth Disorders;
Growth Hormone;
Humans;
Klinefelter Syndrome;
Male*;
Marfan Syndrome;
Phenotype;
Reference Values;
Sex Chromosome Disorders;
Sex Chromosomes
- From:Annals of Pediatric Endocrinology & Metabolism
2015;20(3):170-173
- CountryRepublic of Korea
- Language:English
-
Abstract:
When evaluating the underlying causes of tall stature, it is important to differentiate pathologic tall stature from familial tall stature. Various pathologic conditions leading to adult tall stature include excess growth hormone secretion, Marfan syndrome, androgen or estrogen deficiency, testicular feminization, and sex chromosome anomaly, such as Klinefelter syndrome and XYY syndrome. Men with 47,XYY syndrome can exhibit multiple phenotypes. A 13-year-old boy visited the hospital for evaluation of tall stature. The boy had no other physical abnormalities except tall stature. All biochemical and imaging studies were within the normal ranges. He was diagnosed with XYY syndrome in this chromosome study. When evaluating men with tall stature, XYY syndrome should be ruled out.
