Effect of compound matrine oxygen inhalation on prevention of oral mucosal inflammation for patients after hemopoietic stem cells transplantation
10.3760/cma.j.issn.1674-2907.2016.01.017
- VernacularTitle:雾化吸入复方苦参溶液预防造血干细胞移植口腔黏膜炎的效果
- Author:
Binlian YAO
1
;
Jieying ZHOU
;
Wangfang SHEN
;
Shuifen WU
;
Guan WANG
;
Yuhong ZHOU
Author Information
1. 浙江中医药大学附属第一医院血液科
- Keywords:
Hemopoietic stem cells transplantation;
Stomatitis;
Compound matrine;
Inhalation
- From:
Chinese Journal of Modern Nursing
2016;22(1):66-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of compound matrine oxygen inhalation on prevention of oral mucosal inflammation for patients after hemopoietic stem cells transplantation. Methods A total of 60 patients with allogeneic hemopoietic stem cells transplantation were divided into observation group (30 cases, routine oral nursing and compound matrine oxygen inhalation ) and control group ( 30 cases, routine oral nursing) by random number table. We observed the degree of oral mucosal inflammation and counted the position in two groups during pre-treatment period, low cell stage and convalescence stage from one day before pre-treatment period to 29 days after transplantation. Results The incidences of oral mucosal inflammation were 10. 0%, 56. 7%, 33. 3% in the observation group and 40. 0%, 100. 0%, 93. 3% in the control group during pretreatment period, low cell stage and convalescence stage (Z=3. 406, 5. 720, 5. 002;P<0. 05). There were significant differences in the numbers of occurrence sites between the two groups during pre-treatment period, low cell stage and convalescence stage (Z =2. 866, 6. 596, 5. 448;P <0. 05). Conclusions Compound matrine oxygen inhalation can decrease the degree of oral mucosal inflammation and reduce the occurrence sites of oral mucosal inflammation.
