Research progress of cerebellar transcranial magnetic stimulation in cognitive rehabilitation of Alzheimer's disease

VernacularTitle:小脑经颅磁刺激技术在Alzheimer's病认知康复中的研究进展
Author: Xixi WANG ¹ ; Tong WANG ; Bo SONG
Author Information

1. 210029 南京医科大学附属脑科医院神经内科
Keywords: cerebellum; Alzheimer's disease; non-invasive regulation; transcranial magnetic stimulation
From: Journal of Clinical Neurology 2024;37(4):308-310
CountryChina
Language:Chinese
Abstract: Alzheimer's disease(AD)is a neurodegenerative disease characterized by progressive cognitive dysfunction and behavioral impairment,with a lack of effective drug treatment.Transcranial magnetic stimulation(TMS)is a non-invasive brain stimulation technique,and its role in regulating and improving cognitive function has become increasingly prominent.Previously,the targets of TMS stimulation were focused on the cerebral cortices,but emerging evidence suggests that cerebellum stimulation could not only regulate the motor cortex but also regulate and integrate the distant cognitive-related cerebral regions.Consequently,the cerebellum has gradually emerged as a potential non-invasive therapeutic target for cognitive rehabilitation in AD.This article summarizes the anatomical and functional basis of the cerebellum's involvement in cognitive function regulation,as well as the research progress on TMS modulation of cognitive function mediated by the cerebellum.