Clinicopathologic study of 25 cases of placental chorioangioma

VernacularTitle:胎盘绒毛膜血管瘤25例临床病理分析
Author: Aichun WANG ¹ ; Yaqi MA ; Yun WANG ; Yingnan WANG ; Junling XIE ; Li WANG ; Jing YUAN ; Yiqun GU ; Aijun LIU
Author Information

1. 100080,北京市海淀区妇幼保健院病理科
Keywords: Hemangioma; Chorion; Pregnancy complications; Premature birth
From: Chinese Journal of Pathology 2015;(8):600-602
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinicopathological characteristics , diagnostic criteria and differential diagnosis of placental chorioangioma.Methods Twenty-five cases of placental chorioangioma were analyzed for their clinical data , histomorphology and immumohistochemical staining .Relevant literature was reviewed.Results The average age of the 25 patients was 29 years.Fourteen patients had full-term pregnancy , 10 had preterm labor , and 1 had intrauterine fetal death .Nineteen patients had pregnancy complications.The tumors presented as red or dusty pink nodules with clear borders.The tumor size ranged from 1 to 16 cm.Microscopically , the tumors possessed abundant capillaries or cavernous blood spaces lined by hyperplastic endothelial cells.These cells were positive for CD 34 and Ki-67 index <10%.Conclusions Placental chorioangioma is a rare benign tumor of the placenta , and is associated with various pregnancy complications .Misdiagnosis of cell-rich type tumor should be avoided .