Effect of cognitive behavioural therapy for insomnia combined with stellate ganglion block on insom-nia after corona virus disease-2019
10.12089/jca.2024.08.011
- VernacularTitle:失眠认知行为疗法联合星状神经节阻滞对新型冠状病毒感染后失眠的影响
- Author:
Hua ZHANG
1
;
Qing LI
;
Cheng WANG
;
Lulu ZHANG
;
Yafeng LI
Author Information
1. 330038 南昌市洪都中医院麻醉科
- Keywords:
Cognitive behavioral therapy for insomnia;
Stellate ganglion block;
Corona virus dis-ease-2019;
Insomnia;
Pittsburgh sleep index
- From:
The Journal of Clinical Anesthesiology
2024;40(8):842-847
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of cognitive behavioural therapy for insomnia(CBT-I)combined with stellate ganglion block(SGB)on insomnia after corona virus disease-2019(COVID-19).Methods Eighty-four patients with insomnia after COVID-19 were selected from the anesthesia sleep clinic,26 males and 58 females,aged 18-64 years,BMI 20-32 kg/m2.The patients were randomly divid-ed into two groups:CBT-I combined with SGB(group S)and CBT-I(group C),42 patients in each group.Both groups of patients underwent the same CBT-I regimen for 6 weeks.Patients in group S underwent SGB alternately on both sides every day in the first week,inject 3 ml of 1%lidocaine,1 ml of vitamin B1(50 mg),and 1 ml of vitamin B6(50 mg),totaling 5 ml,and SGB was performed once a week from week 2 to week 6,for a total of 12 times.Group C patients cannot undergo SGB.Record the Pittsburgh sleep quality index(PSQI)scores of patients before treatment,6 weeks,3 months,and 6 months after treatment.Record the insomnia severity index(ISI),Athens insomnia scale(AIS)scores,and serum concentrations of cortisol(Cor)and serotonin(5-HT)before and 1 week and 6 weeks after treatment.Record the patient's compliance with the treatment plan.Results Compared with before treatment,the PSQI scores of the two groups of patients significantly decreased at 6 weeks,3 months,and 6 months after treatment(P＜0.05),the ISI score,AIS score,and serum Cor concentration in group S were significantly reduced after 1 week and 6 weeks of treatment(P＜0.05),while the serum 5-HT concentration was significantly increased(P＜0.05),the ISI score,AIS score,and serum Cor concentration in group C were significantly reduced after 6 weeks of treatment(P＜0.05),while the serum 5-HT concentration was significantly increased(P＜0.05).Compared with group C,patients in group S showed a significant decrease in PSQI scores 6 weeks after treatment(P＜0.05),the ISI score,AIS score,and serum Cor concentration in group S were signifi-cantly reduced after 1 week and 6 weeks of treatment(P＜0.05),while the serum 5-HT concentration was significantly increased(P＜0.05),patients in group S showed a significant increase in adherence to the treatment plan(P＜0.05).Conclusion CBT-I combined with SGB can improve short-term sleep quality after COVID-19,and improve patients'compliance with the treatment plan.
