Research advances of esketamine in patients undergoing cardiovascular surgery
10.12089/jca.2024.07.018
- VernacularTitle:艾司氯胺酮在心血管手术中的应用进展
- Author:
Hongyu HUO
1
;
Lu CHE
;
Yuli WU
;
Yiqi WENG
;
Wenli YU
;
Jiangang XU
Author Information
1. 300070 天津医科大学第一中心临床学院
- Keywords:
Esketamine;
Clinical anesthesia;
Cardiovascular surgery;
Cardiac protection
- From:
The Journal of Clinical Anesthesiology
2024;40(7):766-769
- CountryChina
- Language:Chinese
-
Abstract:
Esketamine is a spin isomer of ketamine,which has the triple effect of sedation,analge-sia and amnesia,and is superior to ablative ketamine in terms of efficacy,controllability.It has been widely used in anesthesia,emergency and critical care in Europe and America,and is mostly used for sedation,analgesia and antidepressant in China.Esketamine is used in cardiac surgery to maintain stable hemodynam-ics,reduce the secretion of inflammatory factors and relieve postoperative pain.Its sympathomimetic effect allows it to be used for the induction of anesthesia in patients with hemodynamic instability and acute heart attack.This paper reviews the recent advance in the clinical value and limitations of esketamine in the perio-perative period of cardiovascular surgery and provides a reference for clinicians to use esketamine in the perioperative period of cardiovascular surgery.
