Clinical pathological analysis of adenomatoid tumor in uterus and ovaries
10.3760/j.issn:0529-5807.2001.01.012
- VernacularTitle:子宫和卵巢腺瘤样瘤的临床病理分析
- Author:
Li ZHU
1
;
Baozhu LI
Author Information
1. Beijing Obstetrics and Gynecology Hospital
- From:
Chinese Journal of Pathology
2001;30(1):43-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the immunohistochemical feature and the differential diagnosis of adenomatoid tumors in uterus and ovaries. Methods Clinical pathological analysis and immunohistochemical studies were performed on 24 cases of adenomatoid tumors in the uterus and ovaries. Results Of the 24 cases, 21 cases were in the uterus, 2 cases in the ovaries and 1 cases in both the uterus and the ovary. Grossly, the mean diameter of the 22 uterus tumors was 2.2 cm, ranging from 0.2～5.5 cm. 14 (63.6%) were located in the subserosa or near by the subserosa of the uterine cornua. The other 8 tumors located in the myometrium. The cut surface presented a nodular pattern with grayish white or yellowish in color, partially cystic. 3 ovarian tumors became all cystic, without a clear-cut margin from the surroundings. Microscopically, the tumor consisted of various gland-like structure or luminal spaces lined with flat, cuboidal or low columnar cells, similar to blood vessels in structure. Among the tumor cells, there were scattered vesicular cells with large or small vacuoles, but no nuclear atypia and mitotic figures detected. Immunohistochemical staining showed the tumor cells positive for vimentin, AE1/AE3 and calretinin, but negative for F VIII-Rag. S-100 and EMA were positive in 20 (83.3%) and 4 (16.7%) cases respectively. Conclusion Adenomatoid tumor of the female genital tract is mesothelial in origin and uterus was considered as the most common site of occurance Immunohistochemcal phenotypes can be used as an important evidence for differential diagnosis. The biological behavior of adenomatoid tumor is benign and with a good prognosis.
