Effect of Semen Quality in the Different Type of Chronic Prostatitis
10.3969/j.issn.1001-1420.2009.07.014
- VernacularTitle:不同分型的慢性前列腺炎对精液质量的影响
- Author:
YUAN RUNQIANG
1
;
YANG ZHIZHAO
;
ZHENG SHAOBIN
;
QIU SHAOPENG
;
LI XINMIN
;
ZHOU HUAKUO
;
SHI YINGJING
Author Information
1. 南方医科大学南方医院
- Keywords:
chronic prostatitis;
autoimmune;
semen-quality
- From:
Journal of Clinical Urology
2009;24(7):522-526
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate whether different type of chronic prostatitis could have a deleterious effect on semen quality. Methods: Forty-nine patients diagnosed as suffering from chronic prostatitis were included and di-vided into groups according to the presence of infection and/or cellular autoimmune response against prostate anti-gens. Healthy normal individuals were included as controls. Measurements for sperm concentration, motility, morphology, prostate and seminal vesicle markers, antisperm antibodies, white blood cells and pro-inflammatory cytokines were performed accordingly. Results:The most severe abnormalities were found in patients with no evi-dent infection and an autoimmune response against prostate antigens. Moreover, significantly increased levels of pro-inflammatory cytokines were detected in seminal plasma from these patients. Conclusions: This study shows that chronic prostatitis patients with cellular autoimmune response to prostate antigens present important altera-tions in their semen quality parameters and may affect male fertility.
