Postoperative usage of α-interferon in the treatment of renal cell carcinoma
10.3969/j.issn.1001-1420.2001.06.009
- VernacularTitle:α-干扰素在肾癌根治术后的应用
- Author:
Wei ZHU
1
;
Jiexin FU
;
Jianan LI
;
Bochuan CHEN
;
Gang YI
Author Information
1. 广西南宁市第一人民医院
- From:
Journal of Clinical Urology
2001;16(6):261-262
- CountryChina
- Language:Chinese
-
Abstract:
Purperse:To study the effect of α interferon in the treatment of renal cell carcinoma after radical nephrectomy.Methods:From Jan 1988 to Jan 1998,46 cases of renal cell carcinoma were randomized into two groups: the study group were treated by radical nephrectomy and α-interferon while the control group with radical nephrectomy alone.Results:The T lymphocyte subsets CD3,CD4,CD8,the ratio of CD4/CD8 are significantly different berfore and after treatment in the study group (P＜0.05); the 3 year(90.5%) and 5 year (89.5%) survival rate in patients of the study group are higher than that of the control group (P＜0.05).Conclusions:α-interferon therapy after radical nephrectomy can restore celluar immunity so as to enhance the treatment efficacy.
