Effect and significance of bFGF for patients of the idiopathic oligoasthenospermia
10.3969/j.issn.1001-1420.2000.10.012
- VernacularTitle:bFGF促进特发性少弱精子症生精细胞增殖超微结构改善及临床观察
- Author:
Xue-Liang CHANG
1
;
Jian-Zhang LIE
;
Guang-Zeng CAI
Author Information
1. the Second Affiliated Hospital of Hebei Medical University
- Keywords:
Basic fibroblast growth factor Oligospermia Treatment
- From:
Journal of Clinical Urology
2000;15(10):460-462
- CountryChina
- Language:Chinese
-
Abstract:
Purpose :To study the effect of bFGF on the idiopathic oligoasthenospermia. Methods:bFGF wasused for 34 patients with idiopathic oligoasthenospermia in the male infertility. The immunohistochemical tech-nique, radioimmunoassay, electromicroscope technique and semen quality analysis were used to investigate thestructure and function of testile of patients. Results: bFGF could promote the proliferation of spermatogenouscells, improve arrangement of cells and ultrastructure of testile. All patients semen were improved. Sexual hor-mones (PRL, FSH, LH, T) in serum araised. The ability of reproduction of patients was increased consequent-ly. Conclusions:bFGF is an effective drug for patients with idiopathic oligoasthenospermia in the male infertility.
