Clinical study of freezing-dried and irradiated vascular allografts for constructing vascular access in hemnodialysis

VernacularTitle:冻干辐射人尸血管移植建立透析通路的研究
Keywords: Blood vessels transplantation Hemodialysis Freezing Desiccation Radiation Cadaver
From: Journal of Clinical Urology 2000;15(10):451-452
CountryChina
Language:Chinese
Abstract: Purpose:To explore the application of vascular allografts for hemodialysis access. Methods:Freezing-dried and irradiated human cadaveric vascular grafts were placed in forearm or upper arm as permanenthemodialysis vascular access in 52 patients with uremia. Results:Immediate patency rate was 100%. All graftswere performed in 3～4 weeks after operation. Among the 44 grafts still being used hitherto, 9 grafts had beenused for 2～3 years, 19 for 1～2 years and 16 in 1 year. Other 8 grafts failured due to complications: thrombosis(5 cases ) 、aneurysm (2 cass) and infection (1 case). Conclusions: Freezing-dried and irradiated vascular allograftswere inexpensive, easy to approach and preserve and, with no antigenicity. The allograft is easy to manage dur-ing surgery and with high patency rate when it was used for hemodialysis access. It was indicated that freezing-dried and irradiated vascular allograft is a good alternative in case of direct A-V fistula failure or inability to per-form a direct A-V anastomosis in patients undergoing hemodialysis.