Effect of persistent psychological intervention on quality of life for patients with ovarian cancer during biotherapy
10.3760/cma.j.issn.1674-2907.2015.20.004
- VernacularTitle:持续心理干预对卵巢癌患者生物治疗期间生活质量的影响
- Author:
Xiangbei HAN
1
;
Wei WANG
;
Lijuan GUO
;
Lingshan WANG
;
Dong YANG
Author Information
1. 130021 长春，吉林省人民医院医学诊治中心
- Keywords:
Ovarian neoplasms;
Quality of life;
Biotherapy;
Psychological intervention
- From:
Chinese Journal of Modern Nursing
2015;(20):2369-2372
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of persistent psychological intervention on negative emotions, immune function and quality of life to patients with ovarian cancer in biotherapy period. Methods A total of 80 ovarian cancer patients were randomly divided into the control group (biotherapy and routine nursing) and the intervention group ( psychological intervention in addition to biotherapy and routine nursing). In the intervention group, Hamilton anxiety scale (HAMA) and Hamilton depression scale (HAMD), and European organization for research and treatment of cancer quality of life questionnaire-30 ( QLQ-C30) were used to measure the psychosomatic reaction, quality of life, and immune level by flow cytometry among ovarian cancer patients during biotherapy 3 weeks after and before psychological interventions. Results Three weeks after intervention, the scores of HAMD (9. 27 ± 3. 15) and HAMA (10. 17 ± 3. 06) in the intervention group were significantly lower than those in control group (16. 93 ± 10. 49) and (18. 97 ± 6. 24) (t = 1. 74,1. 78;P <0. 05), while the scores for general quality of life (71. 52 ±19. 50), the cognitive function (65. 40 ±19. 97) and emotional function (80. 97 ±15. 59) in the intervention group were higher than than these of the control group (t =2.45,2. 67,2. 58;P < 0. 05). The scores for fatigue (34. 76 ± 20. 78), insomnia (41. 75 ± 29. 19) and loss of appetite (59. 57 ± 15. 78) in the intervention group were lower than that of the control group with statistically significant differences (t = 2. 98,3. 27,2. 88;P < 0. 05). Persistent psychological intervention had no significant effect on the immune level of patients ( P > 0. 05). Conclusions Persistent psychological intervention can improve the state of negative emotions and quality of life, and has positive effects on assisting cancer biotherapy.
