Clinical detection and analysis of acquired cytomegalovirus infection in extremely preterm infants
10.13602/j.cnki.jcls.2024.05.06
- VernacularTitle:超早产儿获得性巨细胞病毒感染的临床检测及分析
- Author:
Yan ZHANG
1
;
Hong ZHANG
;
Yanyun WANG
Author Information
1. 南京医科大学附属妇产医院/南京市妇幼保健院新生儿筛查中心,南京 210004
- Keywords:
cytomegalovirus;
transfusion-acquired cytomegalovirus infection;
irradiated red cell;
extremely preterm infant;
extremely low birth weight infant
- From:
Chinese Journal of Clinical Laboratory Science
2024;42(5):348-351
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics of acquired cytomegalovirus infection in extremely preterm infants.Meth-ods The detection results of cytomegalovirus related antibodies in serum samples from 1 072 newborns in the Department of Neonatolo-gy of our hospital from July 1,2023 to September 15,2023 were retrospectively analyzed.Results Among the 1 072 newborns,2 were diagnosed with acquired cytomegalovirus infection.The two newborns were extremely preterm infants(24-27+6 weeks of gestational age)and extremely low birth weight infants(750-999 g).They presented with thrombocytopenia as the initial manifestation.One case was a transfusion-acquired cytomegalovirus infection and the other was a breast milk-acquired cytomegalovirus infection.Conclusion In special populations such as extremely preterm infants,it is necessary to prevent transfusion-acquired cytomegalovirus infection during transfusion therapy,as well as breast milk-acquired cytomegalovirus infection.If necessary,pasteurization should be used before feed-ing.
