Investigation on risk factors for clinical outcomes of patients with bloodstream infections in the emergency intensive care unit
10.13602/j.cnki.jcls.2024.05.03
- VernacularTitle:急诊重症监护室血流感染患者临床结局的风险因子探讨
- Author:
Pei ZHANG
1
;
Ping TAI
;
Kang LIN
;
Wei LI
;
Ling JIN
;
Bangshun HE
;
Xin LIN
Author Information
1. 南京医科大学附属南京医院/南京市第一医院医学检验科,南京 210006
- Keywords:
emergency intensive care unit;
bloodstream infection;
blood culture;
multiple drug resistant bacteria;
precision medica-tion
- From:
Chinese Journal of Clinical Laboratory Science
2024;42(5):332-336
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for the clinical outcomes of patients with bloodstream infections in emergency in-tensive care unit(EICU)and provide a basis for clinical treatment.Methods The medical records and blood culture records of 141 patients with bloodstream infections in the EICU of our hospital from January 2019 to April 2023 were retrospectively collected.The risk factors leading to patients′death were analyzed by the Logistic regression and the relationships between these factors and patients′sur-vival time and outcomes were evaluated by the Cox regression.Results Among the 141 patients with bloodstream infections in the EICU,the mixed bloodstream infections of two or more bacteria(odds ratio[OR]=5.68,95%confidence interval[CI]:1.20-26.98,P＜0.05)and bloodstream infections of multidrug-resistant bacteria(OR=6.39,95%CI:2.78-14.67,P＜0.01)were significantly cor-related with the patients′death.Whether to adjust medication in a timely manner based on drug sensitivity results(hazard ratio[HR]=0.47,95%CI:0.30-0.74)and bloodstream infections of multidrug-resistant bacteria(HR=2.02,95%CI:1.28-3.20)were the risk factors leading to the death of patients with bloodstream infections in the EICU(P＜0.01).Conclusion Early blood culture to identify the pathogenic bacteria and precise medication to control infection can effectively reduce the mortality of patients with bloodstream in-fections in the EICU.
