Research progress of PLGA microspheres in stomatology
10.13591/j.cnki.kqyx.2024.11.015
- VernacularTitle:聚乳酸-羟基乙酸微球在口腔领域的研究进展
- Author:
Yuqian LI
1
;
Jing JIANG
;
Menghan CHEN
;
Yiqian SHAO
;
Jianying FENG
Author Information
1. 浙江中医药大学口腔医学院,浙江 杭州(310053)
- Keywords:
PLGA;
microspheres;
sustained release;
stomatology
- From:
STOMATOLOGY
2024;44(11):876-880
- CountryChina
- Language:Chinese
-
Abstract:
Compared with other drug loading methods,PLGA drug-loaded microspheres have the advantages of sustained and con-trolled release ability,biodegradability,drug release stability,and targeted delivery function,which have become a research hotspot in pharmaceutics.With the improvement of the preparation technology and the quality of microspheres,they have been gradually promoted in clinical practice,and have achieved remarkable results in the treatment of tumors,osteoarthritis,diabetes,eye diseases and so on.However,there is still a lack of systematic review on the application of PLGA microspheres in stomatology.This article aims to intro-duce the clinical application characteristics of PLGA microspheres,and review their application prospect in oral and maxillofacial tumors,temporomandibular joint diseases,periodontitis,caries and alveolar bone defects,so as to provide reference for their applica-tion in stomatology.
