Research progress of treatment strategies for osteoradionecrosis of the jaws
10.13591/j.cnki.kqyx.2024.11.013
- VernacularTitle:放射性颌骨坏死治疗策略研究进展
- Author:
Xirui WANG
1
;
Huiyong ZHU
Author Information
1. 浙江大学医学院附属第一医院口腔颌面外科,浙江 杭州(310058)
- Keywords:
osteonecrosis of the jaws;
mesenchymal stem cells;
virtual surgical planning
- From:
STOMATOLOGY
2024;44(11):864-870
- CountryChina
- Language:Chinese
-
Abstract:
Head and neck cancer is the seventh most common cancer in the world,accounting for about 10%of all malignant tumors.Radiotherapy is an important treatment for head and neck cancer.Osteonecrosis of the jaws(ORNJ)is a refractory complication after ra-diotherapy for head and neck cancer,which often manifests as osteonecrosis of the jaw and soft tissue exposure.The current pathogene-sis of ORNJ has not been fully clarified and its treatment remains challenging.The traditional treatment for this disease is partial resec-tion of necrotic jaw bone and reconstruction with osteocutaneous flap.However,in recent years,some new techniques and ideas have been used to treat the disease.For mild osteoradionecrosis of the jaw,the treatment concept tends to be conservative.This article mainly summarizes the latest research progress at home and abroad,and reviews the pathogenesis,clinical manifestations and treatment strate-gies for osteoradionecrosis of the jaws.
