Research and application progress of gingival mesenchymal stem cells in oral diseases
10.13591/j.cnki.kqyx.2024.07.013
- VernacularTitle:牙龈间充质干细胞治疗口腔疾病研究进展
- Author:
Caitao ZHAO
1
;
Xiaomei XIE
;
Wen YIN
;
Rui CHEN
;
Zhen FAN
;
Chunbo HAO
Author Information
1. 海南医科大学口腔医学院,海南海口(571199)
- Keywords:
gingival mesenchymal stem cells;
tissue engineering;
regenerative medicine
- From:
STOMATOLOGY
2024;44(7):556-560
- CountryChina
- Language:Chinese
-
Abstract:
Gingival mesenchymal stem cells(GMSCs)are a population of mesenchymal stem cells found in the lamina propria of gingi-val tissue and can be isolated not only from healthy gingival tissue but also from hyperplastic or even inflamed gingival tissue.GMSCs have become a hot topic of research in oral disease treatment because of their abundant sources,easy availability,unique immunomod-ulatory properties and multi-directional differentiation potential.GMSCs have been used in the treatment of periodontitis,gingival reces-sion,oral cancer,mandibular defects,peripheral nerve injury repair and so on.To prevent and treat oral diseases,this study will re-view the recent progress of research on the application of GMSCs in oral diseases.