Correlation between largest amplitude of glycemic excursionand short-term prognosis in patients with acute intracerebral hemorrhage
10.3760/cma.j.issn.1671-0282.2024.08.014
- VernacularTitle:最大血糖波动幅度与急性脑出血患者短期预后相关性
- Author:
Pengfei WANG
1
;
Fengqing SONG
;
Jiajun FANG
Author Information
1. 中山大学孙逸仙纪念医院急诊科，广州 510120
- Keywords:
Acute intracranial hemorrhage;
Largest amplitude of glycemic excursion;
Blood glucose variability;
Prognosis
- From:
Chinese Journal of Emergency Medicine
2024;33(8):1161-1165
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between blood glucose levels and blood glucose fluctuations and short-term prognosis in patients with acute cerebral hemorrhage.Methods:A retrospective analysis was conducted on the medical records of patients with acute cerebral hemorrhage admitted to our hospital's Emergency Intensive Care Unit (EICU) from January 2020 to December 2022. Patients were divided into the survival group and death group based on their 28-day survival status. Differences in general information, intravenous blood glucose data, and cerebral hemorrhage-related scoring data between the two groups were compared. Multivariate logistic regression analysis was used to identify independent risk factors, and the predictive significance was verified using the ROC curve.Results:The results of the multivariate logistic regression analysis indicated that intracranial hemorrhage volume of no less than 30 mL, GCS score at admission, systolic blood pressure at admission, and the maximum amplitude of blood glucose fluctuations were correlated with the mortality rate of cerebral hemorrhage cases within 28 days. The relationship between the maximum amplitude of blood glucose fluctuations and death within 28 days was established using the ROC curve, with an area under the curve (AUC) of 0.711 ( P<0.01). Conclusions:The largest amplitude of glucose excursion (LAGE) is an independent risk factor for short-term death and has predictive value for the prognosis in patients with ICH.
